In Vivo Mapping of Neuronal Pathways with Mn Enhanced MRI
X. Zhang and R.E. Jacobs

In vivo MRI mouse images - coronal (C), sagittal (S), and axial (A) slices through a 3D data set. One day previous to MR imaging , Mn was introduced into the right substantia nigra of mouse. Hyperintense areas indicate the neuronal projections and connections traced out by this by non-invasive MRI agent. Arrow head: nigrostriatal projection; arrow: hippocampal formation.